Furthermore, high-quality, randomized and placebo-controlled trials evaluating the efficacy and safety of tamsulosin should be performed. Purify is a premium ad blocker for iOS 9 with a price of 3.99. Purify Fast, Clutter-free Web Browsing in Safari. Another inconvenient thing about 1Blocker is that it doesn’t give you the ability to whitelist a website. In addition, tamsulosin is well tolerated, and its adverse events rarely led to dropouts of patients.Ĭonclusions: Overall, evidence suggests that tamsulosin combined with SWL is safe and effective in enhancing stone expulsion for patients with urolithiasis. The basic app, which is free, only blocks ads from displaying on your device. Furthermore, a shorter expulsion time, reduced occurrence of steinstrasse, fewer incidences of colic, and lower analgesic requirements were observed within the experimental group. The effect estimates did not vary markedly when stratified by follow-up durations but varied by dose of tamsulosin. According to the stone locations (renal, upper and lower ureteral) and sizes (4–10 mm and 11–24 mm), tamsulosin is more useful for lower ureteral stone (RR: 1.28 95% CI, 1.14–1.43) and larger sized stones (RR: 1.49 95% CI, 1.28-1.75). With respect to the different geographic regions, European and American had a high possibility of improvement in stone expulsion (RR: 1.33, 95% CI, 1.19–1.49). Compared with a control group, the experimental group (tamsulosin combined with SWL) showed an increased overall benefit for stone expulsion, with pooled risk ratio (RR) of 1.20 (95% confidence interval, 1.15–1.26). Results: Twenty-one studies (2093 subjects in total) were identified in the current meta-analysis. Meta-analysis was conducted with Review Manager (RevMan), version 5.1. Two reviewers independently assessed trial quality and extracted data. ![]() Methods: A systematic search was performed in PubMed, Cochrane Library, and Embase to identify all relevant randomized controlled trials until January 2015. Therefore, we performed a meta-analysis to provide an update on the clinical efficacy and safety of tamsulosin combined with SWL for urolithiasis. The results from those studies, however, are still inconsistent. ![]() Background and Purpose: Many studies have been conducted to investigate adjunctive tamsulosin therapy after extracorporeal shockwave lithotripsy (SWL) for urolithiasis.
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